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9-cis-Vitamin A acetate-d<sub>5</sub>

" in MedChemExpress (MCE) Product Catalog:

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Click Chemistry:	Azide (4) Alkynes (16)

9921

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

181

Peptides

Inhibitory Antibodies

876

Natural
Products

2970

Recombinant Proteins

2646

Isotope-Labeled Compounds

611

Antibodies

Click Chemistry

Targets Recommended: VD/VDR PIN1 P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-16760S

9-cis-Retinol acetate-d5 9-cis-Vitamin A acetate-d<sub>5sub>; Zuretinol acetate-d<sub>5sub>	Isotope-Labeled Compounds
9-cis-Retinol acetate-d₅ is the deuterium labeled 9-cis-Retinol acetate. 9-cis-Retinol acetate is a retinal derivative[1][2].

HY-N8356A

9-cis-Vitamin A palmitate 9-cis-Retinyl palmitate	Endogenous Metabolite	Others
9-cis-Vitamin A palmitate (9-cis-Retinyl palmitate) is a 9-cis isomer formed by vitamin A palmitate in corn flakes. 9-cis-Vitamin A palmitate has a biological activity of 26% of all-trans-vitamin A palmitate, the most biologically ac-tive form of vitamin A .

HY-16760

9-cis-Retinol acetate

9-cis-Vitamin A acetate; Zuretinol acetate
Others Others

9-cis-Retinol acetate is a retinal derivative.

9-cis-Retinol acetate 9-cis-Vitamin A acetate; Zuretinol acetate	Others	Others
9-cis-Retinol acetate is a retinal derivative.

HY-RS13999

SUB1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SUB1 Human Pre-designed siRNA Set A SUB1 Human Pre-designed siRNA Set A

HY-10844S1

Pretomanid-d5 PA-824-d<sub>5sub>; (S)-PA 824-d<sub>5sub>	Antibiotic Bacterial Isotope-Labeled Compounds	Infection Cancer
Pretomanid-d₅ is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.

HY-146227

DNA topoisomerase II inhibitor 1	Topoisomerase Apoptosis	Cancer
DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase .

HY-B1203AS

Fludrocortisone acetate-d5 9α-Fludrocortisone acetate-d<sub>5sub>; 9α-Fluorcortisol acetate-d<sub>5sub>	Isotope-Labeled Compounds Mineralocorticoid Receptor Autophagy	Inflammation/Immunology
Fludrocortisone acetate-d₅ is deuterium labeled Fludrocortisone acetate.

HY-W102356S2

Phenethyl acetate-d5

PhePhenethyl alcohol, acetate-d<sub>5sub>
Isotope-Labeled Compounds

Phenethyl acetate-d₅ is deuterated labeled Phenethyl acetate.

Phenethyl acetate-d5 PhePhenethyl alcohol, acetate-d<sub>5sub>	Isotope-Labeled Compounds
Phenethyl acetate-d₅ is deuterated labeled Phenethyl acetate.

HY-B0579S2

Cyclosporin A acetate-d4 Cyclosporine A acetate-d<sub>4sub>; Ciclosporin A acetate-d<sub>4sub>; CsA acetate-d<sub>4sub>	Isotope-Labeled Compounds Calcineurin	Inflammation/Immunology
Cyclosporin A acetate-d₄ (Cyclosporine A acetate-d₄; Ciclosporin A acetate-d₄) is a deuterium labeled Cyclosporin A (HY-B0579) . Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC₅₀ of 5 nM . Cyclosporin A also inhibits CD11a/CD18 adhesion .

HY-N0679S4

Retinyl acetate-d4 Retinol acetate-d<sub>4sub>; Vitamin A acetate-d<sub>4sub>	Isotope-Labeled Compounds	Cancer
Retinyl acetate-d₄ is the deuterium labeled Retinyl acetate[1]. Retinyl acetate is a synthetic acetate ester form derived from retinol and has potential antineoplastic and chemo preventive activities[2].

HY-B0469S

Medroxyprogesterone acetate-d3 Medroxyprogesterone 17-acetate-d<sub>3sub>; Farlutin-d<sub>3sub>	Progesterone Receptor Androgen Receptor Glucocorticoid Receptor	Endocrinology Cancer
Medroxyprogesterone acetate-d₃ is deuterium labeled Medroxyprogesterone acetate. Medroxyprogesterone acetate is a widely used synthetic steroid by its interaction with progesterone, androgen and glucocorticoid receptors[1].

HY-13777S

Zoledronic acid-d5 Zoledronate-d<sub>5sub>; CGP 42446-d<sub>5sub>; CGP42446A-d<sub>5sub>; ZOL 446-d<sub>5sub>	Bacterial Apoptosis Autophagy Isotope-Labeled Compounds	Metabolic Disease Cancer
Zoledronic acid-d₅ is deuterated labeled Zoledronic Acid (HY-13777). Zoledronic Acid (Zoledronate) is a third-generation bisphosphonate (BP), with potent anti-resorptive activity. Zoledronic Acid inhibits the differentiation and apoptosis of osteoclasts. Zoledronic Acid also has anti-cancer effects .

HY-W102356S

Phenethyl acetate-d3

Phenethyl alcohol, acetate-d<sub>3sub>
Isotope-Labeled Compounds Others

Phenethyl acetate-d₃ is the deuterium labeled Phenethyl acetate[1].

Phenethyl acetate-d3 Phenethyl alcohol, acetate-d<sub>3sub>	Isotope-Labeled Compounds	Others
Phenethyl acetate-d₃ is the deuterium labeled Phenethyl acetate[1].

HY-109592S

Imidaprilate-d5 6366A-d<sub>5sub>; Imidaprilat-d<sub>5sub>	Isotope-Labeled Compounds Angiotensin-converting Enzyme (ACE)	Cardiovascular Disease
Imidaprilate-d₅ is deuterium labeled Imidaprilate. Imidaprilate is an active metabolite of TA-6366, acts as a potent angiotensin converting enzyme (ACE) inhibitor, with an IC50 of 2.6 nM, and is used in the research of hypertensive disease.

HY-B1710S

Norethindrone acetate-d8 19-Norethindrone acetate-d<sub>8sub>	Isotope-Labeled Compounds Progesterone Receptor	Cardiovascular Disease Inflammation/Immunology Endocrinology
Norethindrone acetate-d₈ is the deuterium labeled Norethindrone acetate. Norethindrone acetate is a female hormone used for the research of endometriosis[1]. Norethindrone acetate-d8 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B0184S1

Felbamate-d5 Felbamyl-d<sub>5sub>; Felbatol-d<sub>5sub>; Taloxa-d<sub>5sub>	iGluR	Neurological Disease
Felbamate-d₅ is the deuterium labeled Felbamate[1]. Felbamate (W-554) is a potent nonsedative anticonvulsant whose clinical effect may be related to the inhibition of N-methyl-D-aspartate (NMDA)[2][3].

HY-W016481S

4-Methoxybenzyl acetate-d3

Anisyl acetate-d<sub>3sub>
Isotope-Labeled Compounds Others

4-Methoxybenzyl acetate-d₃ is deuterated labeled cis-3-Hexenyl Acetate.

4-Methoxybenzyl acetate-d3 Anisyl acetate-d<sub>3sub>	Isotope-Labeled Compounds	Others
4-Methoxybenzyl acetate-d₃ is deuterated labeled cis-3-Hexenyl Acetate.

HY-17621S

Sparsentan-d5 RE-021-d<sub>5sub>; DARA-a-d<sub>5sub>	Isotope-Labeled Compounds Angiotensin Receptor Endothelin Receptor	Cardiovascular Disease Endocrinology
Sparsentan-d₅ is deuterium labeled Sparsentan. Sparsentan (RE-021) is a highly potent dual angiotensin II and endothelin A receptor antagonist with Kis of 0.8 and 9.3 nM, respectively[1].

HY-W015304S

2-Ethylhexyl acetate-d17

Octyl acetate-d<sub>17sub>
Isotope-Labeled Compounds Others

2-Ethylhexyl acetate-d₁₇ is the deuterium labeled 2-Ethylhexyl acetate[1].
HY-W343292S1

2-Methylbutyl acetate-d3

Methyl-2-butyl-acetate fcc-d<sub>3sub>
Isotope-Labeled Compounds

2-Methylbutyl acetate-d₃ is deuterated labeled 2-Methylbutyl acetate.

2-Ethylhexyl acetate-d17 Octyl acetate-d<sub>17sub>	Isotope-Labeled Compounds	Others
2-Ethylhexyl acetate-d₁₇ is the deuterium labeled 2-Ethylhexyl acetate[1].

2-Methylbutyl acetate-d3 Methyl-2-butyl-acetate fcc-d<sub>3sub>	Isotope-Labeled Compounds
2-Methylbutyl acetate-d₃ is deuterated labeled 2-Methylbutyl acetate.

HY-16560S

Camptothecin-d5 Campathecin-d<sub>5sub>; (S)-(+)-Camptothecin-d<sub>5sub>; CPT-d<sub>5sub>	Topoisomerase ADC Cytotoxin MicroRNA Influenza Virus Apoptosis Fungal Antibiotic	Infection Cancer
Camptothecin-d₅ is the deuterium labeled Camptothecin. Camptothecin (CPT), a kind of alkaloid, is a DNA topoisomerase I (Topo I) inhibitor with an IC50 of 679 nM[1]. Camptothecin (CPT) exhibits powerful antineoplastic activity against colorectal, breast, lung and ovarian cancers, modulates hypoxia-inducible factor-1α (HIF-1α) activity by changing microRNAs (miRNA) expression patterns in human cancer cells[2][3].

HY-B0715S2

Pentoxifylline-d5 BL-191-d<sub>5sub>; PTX-d<sub>5sub>; Oxpentifylline-d<sub>5sub>	Phosphodiesterase (PDE) Autophagy HIV	Cardiovascular Disease Cancer
Pentoxifylline-d₅ is the deuterium labeled Pentoxifylline. Pentoxifylline (BL-191), a haemorheological agent, is an orally active non-selective phosphodiesterase (PDE) inhibitor, with immune modulation, anti-inflammatory, hemorheological, anti-fibrinolytic and anti-proliferation effects. Pentoxifylline can be used for the research of peripheral vascular disease, cerebrovascular disease and a number of other conditions involving a defective regional microcirculation[1][2][3].

HY-14649S4

Retinoic acid-d5 Vitamin A acid-d<sub>5sub>; all-trans-Retinoic acid-d<sub>5sub>; ATRA-d<sub>5sub>	Isotope-Labeled Compounds RAR/RXR PPAR	Cancer
Retinoic acid-d₅ is the the deuterium labeled Retinoic acid (HY-14649). Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC₅₀s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with K_d of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha ^[5].

HY-107819S

5α-Cholestan-3β-ol-d5 Dihydrocholesterol-d<sub>5sub>; 5α-Cholestanol-d<sub>5sub>; NSC 18188-d<sub>5sub>	Isotope-Labeled Compounds Endogenous Metabolite
5α-Cholestan-3β-ol-d₅ is the deuterium labeled 5α-Cholestan-3β-ol. 5α-Cholestan-3β-ol is a derivitized steroid compound[1].

HY-N0573S

Umbelliferone-d5 7-Hydroxycoumarin-d<sub>5sub>; Hydrangin-d<sub>5sub>; NSC 19790-d<sub>5sub>	Endogenous Metabolite Apoptosis	Cancer
Umbelliferone-d₅ is the deuterium labeled Umbelliferone. Umbelliferone (7-Hydroxycoumarin), a natural product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent.

HY-W022036S

2-Ethoxyphenol-d5

Guaethol-d<sub>5sub>; Guethol-d<sub>5sub>; NSC 180-d<sub>5sub>
Isotope-Labeled Compounds Others

2-Ethoxyphenol-d₅ is the deuterium labeled 2-Ethoxyphenol[1].

2-Ethoxyphenol-d5 Guaethol-d<sub>5sub>; Guethol-d<sub>5sub>; NSC 180-d<sub>5sub>	Isotope-Labeled Compounds	Others
2-Ethoxyphenol-d₅ is the deuterium labeled 2-Ethoxyphenol[1].

HY-66005S5

Acetaminophen-d5 Paracetamol-d<sub>5sub>; 4-Acetamidophenol-d<sub>5sub>; 4'-Hydroxyacetanilide-d<sub>5sub>	Isotope-Labeled Compounds	Others
Acetaminophen-d₅ is deuterated-labeled Acetaminophen.

HY-16562AS

Irinotecan-d5 hydrochloride (+)-Irinotecan-d<sub>5sub> hydrochloride; CPT-11-d<sub>5sub> hydrochloride; VAL-413-d<sub>5sub>	Autophagy Topoisomerase Isotope-Labeled Compounds	Cancer
Irinotecan-d₅ hydrochloride is deuterated labeled Irinotecan hydrochloride (HY-16562A). Irinotecan hydrochloride ((+)-Irinotecan hydrochloride) is a topoisomerase I inhibitor mainly used to treat colon cancer and rectal cancer .

HY-B1207S

Urethane-d5 Ethyl carbamate-d<sub>5sub>; Carbamic acid ethyl ester-d<sub>5sub>; Ethylurethane-d<sub>5sub>	Bacterial Parasite	Infection Neurological Disease Cancer
Urethane-d₅ is the deuterium labeled Urethane. Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress bacterial, protozoal, sea urchin egg, and plant tissue growth in vitro[1].

HY-77839S

Cortodoxone-d5 11-Deoxycortisol-d<sub>5sub>; cortexolone-d<sub>5sub>; Reichstein's substance S-d<sub>5sub>	Isotope-Labeled Compounds Glucocorticoid Receptor Endogenous Metabolite	Inflammation/Immunology Endocrinology
Cortodoxone-d₅ is the deuterium labeled Cortodoxone.

HY-14814S

Delafloxacin-d5 RX-3341-d<sub>5sub>; WQ-3034-d<sub>5sub>; ABT492-d<sub>5sub>	Isotope-Labeled Compounds Bacterial Antibiotic	Infection
Delafloxacin-d₅ is deuterium labeled Delafloxacin. Delafloxacin (RX-3341; WQ-3034; ABT492) is a broad-spectrum fluoroquinolone antibiotic. Delafloxacin has a broad spectrum of activity that includes drug-resistant Staphylococcus aureus, Streptococcus pneumoniae, and Klebsiella pneumonia[1].

HY-13636S1

Fulvestrant-d5

ICI 182780-d<sub>5sub>; ZD 9238-d<sub>5sub>; ZM 182780-d<sub>5sub>
Isotope-Labeled Compounds Others

Fulvestrant-d5 is a isotope of Fulvestrant .
HY-B1342S4

Retinol-d5

Vitamin A1-d<sub>5sub>; all-trans-Retinol-d<sub>5sub>
Isotope-Labeled Compounds Others

Retinol-d₅ is the deuterium labeled Retinol[1].

Fulvestrant-d5 ICI 182780-d<sub>5sub>; ZD 9238-d<sub>5sub>; ZM 182780-d<sub>5sub>	Isotope-Labeled Compounds	Others
Fulvestrant-d5 is a isotope of Fulvestrant .

Retinol-d5 Vitamin A1-d<sub>5sub>; all-trans-Retinol-d<sub>5sub>	Isotope-Labeled Compounds	Others
Retinol-d₅ is the deuterium labeled Retinol[1].

HY-W014612S

Eugenol acetate-d3 Acetyleugenol-d<sub>3sub>	Bacterial Endogenous Metabolite Fungal Isotope-Labeled Compounds	Cancer
Eugenol acetate-d₃ is deuterated labeled Decyl aldehyde (HY-W012570). Decyl aldehyde is a simple ten-carbon aldehyde. Decyl aldehyde is a bacterial luciferase substrate.

HY-B0200S

Cephalexin-d5 Cefalexin-d<sub>5sub>; Cephacillin-d<sub>5sub>	Antibiotic Bacterial	Infection
Cephalexin-d₅ is deuterium labeled Cephalexin. Cephalexin (Cefalexin; Cephacillin) is a potent, orally active and the first-generation cephalosporin antibiotic. Cephalexin kills gram-positive and some gram-negative bacteria by disrupting the growth of the bacterial cell wall. Cephalexin monohydrate is used for the research of pneumonia, strep throat, and bacterial endocarditis, et al[1].

HY-B0178AS1

Guanidine-d5 hydrochloride Guanidinium-d<sub>5sub> chloride; Aminoformamidine-d<sub>5sub> hydrochloride	Endogenous Metabolite
Guanidine-d₅ (hydrochloride) is the deuterium labeled Guanidine hydrochloride[1]. Guanidine hydrochloride (Guanidinium chloride) a strong chaotrope, is also a strong denaturant of proteins[2][3].

HY-B1214S

Prednisolone acetate-d8 Prednisolone 21-acetate-d<sub>8sub>	Isotope-Labeled Compounds Glucocorticoid Receptor	Inflammation/Immunology
Prednisolone acetate-d₈ is the deuterium labeled Prednisolone acetate. Prednisolone acetate (Prednisolone 21-acetate) is an adrenal cortico hormones, with anti-inflammatory, anti-allergic and immune suppressive effects.

HY-N0570S1

Hydroxytyrosol-d5 DOPET-d<sub>5sub>; 3,4-Dihydroxyphenethyl alcohol-d<sub>5sub>; 3-Hydroxytyrosol-d<sub>5sub>	Endogenous Metabolite Bacterial Fungal	Infection Inflammation/Immunology Cancer
Hydroxytyrosol-d₅ is the deuterium labeled Hydroxytyrosol. Hydroxytyrosol (DOPET) is a phenolic compound drawn from the olive tree and its leaves with anti-oxidant, anti-atherogenic, anti-thrombotic, antimicrobial, anti-inflammatory and anti-tumour effects[1][2].

HY-B0941S

6-Benzylaminopurine-d5 Benzyladenine-d<sub>5sub>; 6-BAP-d<sub>5sub>; N6-Benzyladenine-d<sub>5sub>	Endogenous Metabolite Isotope-Labeled Compounds	Others
6-Benzylaminopurine-d₅ is the deuterium labeled 6-Benzylaminopurine. 6-Benzylaminopurine is a cytokinin[1].

HY-B0878S

Halobetasol propionate-d5 BMY-30056-d<sub>5sub>; CGP-14458-d<sub>5sub>; Ulobetasol propionate-d<sub>5sub>	Isotope-Labeled Compounds	Others
Halobetasol propionate-d₅ is deuterium labeled Halobetasol (propionate).

HY-B1290S2

2-Phenylethanol-d5 Phenylethyl alcohol-d<sub>5sub>; Phenethyl alcohol-d<sub>5sub>; Benzyl carbinol-d<sub>5sub>	Bacterial Virus Protease Antibiotic	Infection
2-Phenylethanol-d₅ is the deuterium labeled 2-Phenylethanol[1]. 2-Phenylethanol (Phenethyl alcohol), extracted from rose, carnation, hyacinth, Aleppo pine, orange blossom and other organisms, is a colourless liquid. It has a pleasant floral odor and also an autoantibiotic produced by the fungus Candida albicans[2]. It is used as an additive in cigarettes and also used as a preservative in soaps due to its stability in basic conditions.

HY-B1832S

Prednisone acetate-d3 Prednisone 21-acetate-d<sub>3sub>	Glucocorticoid Receptor	Inflammation/Immunology Endocrinology
Prednisone acetate-d₃ is the deuterium labeled Prednisone acetate. Prednisone acetate (Prednisone 21-acetate), the acetate salt form of prednisolone, is a glucocorticoid receptor agonist with anti-inflammatory and immunomodulating properties[1].

HY-125833

Alpha-Naphthoflavone 5 Publications Verification	Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis	Cancer
Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis .

HY-W015710S

cis-3-Hexenyl Acetate-d2

cis-3-Hexene-1-Yl acetate-d<sub>2sub>
Isotope-Labeled Compounds Others

cis-3-Hexenyl Acetate-d₂ is deuterated labeled 2-Benzylideneheptanal.

cis-3-Hexenyl Acetate-d2 cis-3-Hexene-1-Yl acetate-d<sub>2sub>	Isotope-Labeled Compounds	Others
cis-3-Hexenyl Acetate-d₂ is deuterated labeled 2-Benzylideneheptanal.

HY-D0272S

2,3,4-Trihydroxybenzophenone-d5 Alizarin Yellow A-d<sub>5sub>; Alizarine Yellow A-d<sub>5sub>	Isotope-Labeled Compounds	Others
2,3,4-Trihydroxybenzophenone-d₅ is the deuterium labeled 2,3,4-Trihydroxybenzophenone[1].

HY-B0346S

Propylthiouracil-d5 6-n-Propylthiouracil-d<sub>5sub>; 6-Propyl-2-thiouracil-d<sub>5sub>; PTU-d<sub>5sub>	Isotope-Labeled Compounds	Endocrinology
Propylthiouracil-d₅ is the deuterium labeled Propylthiouracil. Propylthiouracil (6-Propyl-2-thiouracil) is a thyroperoxidase and 5'-deiodinase inhibitor.

HY-12222S

Obeticholic acid-d5 INT-747-d<sub>5sub>; 6-ECDCA-d<sub>5sub>; 6-Ethylchenodeoxycholic acid-d<sub>5sub>	FXR Autophagy	Others
Obeticholic acid-d₅ is the deuterium labeled Obeticholic acid. Obeticholic acid (INT-747) is a potent, selective and orally active FXR agonist with an EC50 of 99 nM. Obeticholic acid has anticholeretic and anti-inflammation effect. Obeticholic acid also induces autophagy[1][2][3].

HY-12760S

Indoramin-d5 Indoramine d<sub>5sub>; Wy-21901 d<sub>5sub>	Isotope-Labeled Compounds Adrenergic Receptor	Cardiovascular Disease
Indoramin-d₅ is deuterium labeled Indoramin, which is a piperidine antiadrenergic agent.

HY-14648S

Dexamethasone-d5 Hexadecadrol-d<sub>5sub>; Prednisolone F-d<sub>5sub>	Glucocorticoid Receptor SARS-CoV Autophagy Complement System Mitophagy Bacterial Antibiotic	Infection Inflammation/Immunology Endocrinology Cancer
Dexamethasone-d₅ is the deuterium labeled Dexamethasone. Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18 expression on monocytes. Dexamethasone is highly effective in the control of COVID-19 infection. Dexamethasone inhibits production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses[1][2].

HY-17043S1

Loratadine-d5 Loratidine-d<sub>5sub>; SCH 29851-d<sub>5sub>	Isotope-Labeled Compounds Histamine Receptor	Infection Inflammation/Immunology Endocrinology
Loratadine-d₅ is the deuterium labeled Loratadine. Loratadine (SCH-29851) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM. Loratadine has anti-dengue-virus (DENV) activity. Loratadine can inhibit immunologic release of inflammatory mediators.

Cat. No.	Product Name	Type

HY-D1633

4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate	Fluorescent Dyes/Probes
4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate is a fluorescent dye. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate can be used in the diagnosis of mucopolysaccharidosis IV A by detecting activity of galactose-6-sulphate sulphatase .

HY-D1633A

4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium	Fluorescent Dyes/Probes
4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium is a fluorescent dye. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium can be used in the diagnosis of mucopolysaccharidosis IV A by detecting activity of galactose-6-sulphate sulphatase .

HY-W019823

4-MUNANA

Fluorescent Dyes/Probes

4-MUNANA is a fluorescent substrate used for neuraminidase activity assay .

HY-D1594

BODIPY TR Cadaverine	Fluorescent Dyes/Probes
BODIPY TR Cadaverine, a cadaverine derivative, is a red fluorescent dye. BODIPY TR Cadaverine can be used in a a highly sensitive and robust fluorescent displacement assay, which binds to native LPS strongly, specifically recognizing lipid A, and is competitively displaced by compounds displaying an affinity for lipid A .

HY-D1544

Uniblue A sodium

Fluorescent Dyes/Probes

Uniblue A sodium is a reactive protein stain that can be used in the covalent pre-gel staining of the protein (Ex=594 nM) .

HY-118462

Coelenteramine 400a

Coelenterazine 400a; Bisdeoxycoelenterazine

Dyes

Coelenteramine 400a (Coelenterazine 400a), a derivative of Coelenterazine, is a Renilla luciferase (RLuc) substrate. In the presence of Coelenteramine 400a, RLuc can emit blue light at 395 nm . Coelenterazine 400a will causes color change in the bioluminescence reaction of Rluc by replacing the sulfur and oxygen heteroatoms of the methylene bridge. Coelenterazine 400a provides higher signal resolution and can be used in the research of bioluminescence resonance energy transfer (BRET) .

HY-15764G

A 419259 (GMP) RK-20449 (GMP)	Fluorescent Dye
A 419259 GMP is the GMP grade A 419259 (HY-15764), inducing cell apoptosis. GMP-grade small molecules can be used as auxiliary reagents in cell therapy. A 419259 (RK-20449) is a broad-spectrum pyrrole-pyrimidine inhibitor targeting Src, Lck, and Lyn with IC₅₀s of 9 nM, <3 nM, and <3 nM, respectively .

HY-D0947

Azure A chloride	Dyes
Azure A (chloride) is a phenothiazine dye. Azure A (chlorine) is formed by oxidation of methylene blue and has strong metachromatic. Azure A (chlorine) can be used for the study of stains and redox media for electrochemical biosensing .

HY-D1840

Tyramide Amplification Buffer

Dyes

Tyramide Amplification Buffer is a ready-to-use buffer primarily intended for immunostaining of cells and tissues by the technique of tyramide signal amplification (TSA). TSA Technology is based on a tyrosinase labeling system that reacts a tyrosine-labeled antibody with a fluorescently labeled tyramide using peroxidase to form a highly amplified fluorescent signal. For example, horseradish peroxidase (HRP) can catalyze the reaction of tyrosine and hydrogen peroxide under milder conditions to generate epoxy groups. Epoxy groups promote the binding of tyramide to adjacent amino acids to form fluorescently labeled products .

HY-D1472

Azure A eosinate	Dyes
Azure A eosinate is a dye for hematological and histological applications. Azure A eosinate can be used as new photosensitizer prototypes to determine growth inhibition of Candida albicans .

HY-D0356

Eriochrome Black A

Dyes

Eriochrome Black A is an azo dye that can be removed from water by an adsorbent made of magnetic NiFe2O4 nanoparticles.

HY-10432G

A 83-01 (GMP)	Fluorescent Dye
A 83-01 (GMP) is A 83-01 (HY-10432) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. A 83-01 is a potent *ALK4/5/7* inhibitor .

HY-D1772

Nile Blue A perchlorate

Fluorescent Dyes/Probes

Nile Blue A perchlorate is a laser dye used for pulsed and CW operations.
HY-129042

Cibacron Blue 3G-A

1 Publications Verification

Dyes

Cibacron Blue 3G-A is an anthraquinone dye, inhibits the R46 β-lactamase with a K_i value of 1.2 uM .

HY-D1385

JF526–Pepstatin A TFA	Fluorescent Dyes/Probes
JF526–Pepstatin A TFA is a fluorescent dye that can be used for lysosomal staining in live cells. The excitation maximum is 530 nm and the emission maximum is 549 nm .

HY-D1823

Vari Fluor 647A Carboxylic acid（free acid） VF 647A Carboxylic acid（free acid）	Dyes
Vari Fluor 647A Carboxylic acid (VF 647A Carboxylic acid) free acid is a carboxylic acid derivative of Vari Fluor. Vari Fluor carboxylic acid derivatives are unactivated labeled fluorescent dyes for protein, antibody, and polysaccharide labeling that require carboxylic acid activation for use .

HY-101900

Nile Blue A sulfate Nile blue sulfate	Fluorescent Dyes/Probes
Nile Blue A (Nile blue sulfate) is used to differentiate melanins and lipofuscins. It is also useful for staining fats and preparation of an amperometric glucose sensor .

Cat. No.	Product Name	Target	Research Area

HY-P99294

Ganitumab AMG 479; Human Anti-IGF1R Recombinant Antibody	IGF-1R	Cancer
Ganitumab (AMG 479) is a recombinant human monoclonal antibody to the human type 1 insulin-like growth factor receptor (IGF1R). Ganitumab recognizes murine IGF1R with sub-nanomolar affinity (K_D=0.22 nM) and inhibits the interaction of murine IGF1R with IGF1 and IGF2. Ganitumab can be used in research of cancer .

HY-P99277

Actoxumab Anti-C. difficile Toxin A Recombinant Antibody	Inhibitory Antibodies	Infection
Actoxumab (Anti-C. difficile Toxin A Recombinant Antibody) is a antitoxin antibody against C. difficile toxin A by neutralizing TcdA. Actoxumab prevents both the damage to the gut wall and the inflammatory response, which are associated with C. difficile. Actoxumab has synergy effect with Bezlotoxumab (HY-P9929) targeting TcdB .

HY-P99863

Dorlimomab aritox 4197X-RA; MDX-RA (ricin A chain) immunotoxin	Inhibitory Antibodies	Others
Dorlimomab aritox (4197X-RA; MDX-RA (ricin A chain) immunotoxin) is a mouse-derived monoclonal antibody conjugated to ricin A .

HY-P99569

Telimomab aritox T101-ricin A chain immunotoxin; T101-RTA	Inhibitory Antibodies	Inflammation/Immunology
Telimomab aritox (T101-ricin A chain immunotoxin) is a mouse monoclonal antibody that linked to the A chain of the ricin protein. Telimomab aritox can be used as an immunosuppressive agent .

HY-P99477

Bevifimod PRTX-100	Inhibitory Antibodies	Cardiovascular Disease Inflammation/Immunology
Bevifimod (PRTX-100) is a highly purified form of Staphylococcal protein A (SpA). Bevifimod can be used for idiopathic thrombocytopenic purpura (ITP) research .

HY-P9940

Emicizumab	Factor VIII	Cardiovascular Disease
Emicizumab is a bispecific monoclonal antibody that bridges activated factor IX and factor X to replace the function of missing activated factor VIII, thereby restoring hemostasis. Emicizumab can be used for hemophilia A research .

HY-P99770

Omodenbamab 514-G3	Bacterial	Infection
Omodenbamab is an anti-SpA (Staphylococcal protein A) human monoclonal antibody with a K_D value of 0.0467 nM. Omodenbamab circumvents a key S. aureus evasion mechanism by targeting the cell wall moiety Protein A (SpA). Omodenbamab can be used in research of S. aureus bloodstream infection .

HY-P99750

Navivumab CT-P23	Influenza Virus	Infection
Navivumab (CT-P23) is an influenza A virus hemagglutinin HA monoclonal antibody. neutralizes H1, H2, H5, and H9 influenza A viruses by binding to the stem fusion domain in HA2 .

HY-P99632

Garetosmab REGN 2477	TGF-β Receptor	Inflammation/Immunology
Garetosmab (REGN 2477) is a fully human IgG4 monoclonal antibody that specifically inhibits activin A. Garetosmab can be used for fibrodysplasia ossificans progressiva (FOP) research .

HY-P9929

Bezlotoxumab	Bacterial	Infection Inflammation/Immunology
Bezlotoxumab is a human monoclonal antibody directed against C. difficile toxin B. Bezlotoxumab binds to C. difficile toxin B preventing intestinal epithelial damage and colitis .

HY-108794

Elosulfase alfa BMN 110; Chondrosulfatase; Chondroitinase; Chondrosulfatases; Chondroitin sulfatase	Inhibitory Antibodies	Others
Elosulfase alfa (BMN 110) is a recombinant form of human N-acetylgalactosamine-6-sulfatase (GALNS). Elosulfase alfa is used as an enzyme replacement therapy for mucopolysaccharidosis IVA (MPS IVA), also known as Morquio A syndrome .

HY-P99571

Tefibazumab INH-H 2002	Inhibitory Antibodies	Infection
Tefibazumab is a humanized IgG1κ monoclonal antibody that binds to the surface-expressed adhesion protein clumping factor A. Tefibazumab can be used for the research of serious Staphylococcus aureus infections .

HY-P99359

Elezanumab ABT-555; AE12-1Y-QL; Anti-RGMA Reference Antibody (elezanumab)	TGF-beta/Smad	Metabolic Disease
Elezanumab (ABT-555; AE12-1Y-QL) is a human monoclonal antibody that selectively targets repulsive guidance molecule A (RGMa). Elezanumab potently inhibited RGMa mediated BMP signalling via the SMAD1/5/8 pathway, with an IC₅₀ around 97 pM. Elezanumab promotes neuroregeneration and neuroprotection in neuronal injury and demyelination models binds N-terminal RGMa, blocks BMP signaling and lacks RGMc cross-reactivity. elezanumab has neuroregenerative and neuroprotective activities without impact on iron metabolism .

HY-P99620

Firivumab CT-P22; CT120	Influenza Virus	Infection
Firivumab (CT-P22; CT120) is a human IgG1 monoclonal influenza A virus hemagglutinin (Anti-IAV HA) antibody. Firivumab is capable of neutralizing H1N1, H5N1, H6N1, H6N2, H8N4, H8N8, H9N2 and H12N7. Firivumab shows protection against H1N1 virus in mice .

HY-P9805

Anti-MERS-3A1 mAb MERS-3A1; MERS Antibody-3A1	SARS-CoV	Infection
Anti-MERS-3A1 mAb (MERS-3A1) is a human monoclonal IgG1 antibody with the high binding affinity produced in CHO cells. Anti-MERS-3A1 mAb bocks the binding of MERS-CoV spike protein to DPP4 receptor .

HY-P99986

Mouse lgG2a (D265A) kappa, Isotype Control	Inhibitory Antibodies	Inflammation/Immunology
Mouse lgG2a (D265A) kappa, Isotype Control, a mouse monoclonal antibody, is an isotype control for mouse lgG2a (D265A) antibody.

HY-P990148

Anti-Mouse VEGF-A Antibody (2G11-2A05)	Inhibitory Antibodies	Others
Anti-Mouse VEGF-A Antibody (2G11-2A05) is a rat-derived IgG2a, κ type antibody inhibitor, targeting to mouse VEGF-A.

HY-P990183

Mouse IgG2a (D265A) kappa, isotype control	Inhibitory Antibodies	Others
Mouse IgG2a (D265A) kappa, isotype control is a mouse-derived IgG2a type antibody inhibitor, targeting to mouse IgG2a.

HY-P9904

Atezolizumab 15+ Cited Publications MPDL3280A	PD-1/PD-L1 Apoptosis Autophagy	Cancer
Atezolizumab (MPDL3280A) is a selective humanized monoclonal IgG1 antibody against programmed death ligand 1 (PD-L1), used for cancer research.

HY-P99033

Mosunetuzumab BTCT-4465A	CD20 CD3	Inflammation/Immunology Cancer
Mosunetuzumab (BTCT-4465A) is a full-length, fully humanized immunoglobulin G1 (IgG1) T-cell-dependent bispecific (TDB) antibody targeting CD20 (B cells) and CD3 (T cells). Mosunetuzumab redirects T cells to engage and eliminate malignant B cells and can be used for the research of relapsed or refractory (R/R) B-cell non-Hodgkin lymphomas (B-NHLs) .

HY-P99237

Sofituzumab

MMUC 1206A
Inhibitory Antibodies Cancer

Sofituzumab (MMUC 1206A) is a humanizedized anti-MUC16 recombinant V-kappa antibody .

HY-P99225

Mirvetuximab M9346A	Antifolate	Cancer
Mirvetuximab (M9346A) is an anti-FOLR1 (folate receptor 1) monoclonal antibody. Mirvetuximab is the antibody moiety of novel folate receptor alpha (FRα)-targeting ADC (Mirvetuximab soravtansine). Mirvetuximab soravtansine can be used in ovarian and other FRα-positive cancer research .

HY-P99386

Vesencumab MNRP-1685A	Complement System	Cancer
Vesencumab (MNRP-1685A) is IG1 antibody against neuropilin-1 (NRP-1). Vesencumab binds to NRP-1 and prevents the subsequent coupling of NRP-1 to VEGFR-2. Vesencumab has anti-angiogenic and anti-neoplastic activities. Vesencumab can be used in the research of metastatic solid tumors, including ovarian cancer .

HY-P99633

Garivulimab BGB-A333	PD-1/PD-L1 Apoptosis	Cancer
Garivulimab (BGB-A333) is a humanized IgG1-variant monoclonal antibody that specifically targets and binds to PD-L1. Garivulimab selectively blocks the interaction of PD-L1 and PD-1. Garivulimab has antitumor activity .

HY-P99962

Surzebiclimab BGB-A425	Mucin	Cancer
Surzebiclimab (BGB-A425) is a humanized IgG1-variant monoclonal antibody against T-cell immunoglobulin and mucin-domain containing-3 (TIM-3). Surzebiclimab binds to the extracellular domain of human Tim-3 with high affinity (K_D=0.36 nM) and specificity. Surzebiclimab can be used in research of cancer .

HY-P99656

Iladatuzumab MCDS0593A	ADC Antibody	Cancer
Iladatuzumab (MCDS0593A) is a humanized IgG1 anti-human CD79B monoclonal antibody. Iladatuzumab can be used to synthesize antibody-drug conjugates (ADC) Iladatuzumab vedotin (DCDS0780A; HY-P99657), which has the potential for B-cell non-Hodgkin lymphoma (B-NHL) research .

HY-P99684

Laprituximab

J2898A
EGFR Cancer

Laprituximab (J2898A) is a humanized IgG1 anti-EGFR antibody that can be used for the synthesis of ADC IMGN289 .

HY-P99793

Orticumab MLDL1278A	LDLR	Inflammation/Immunology
Orticumab (MLDL1278A) is an antibody targeting to oxidized or malondialdehyde-modified lipoprotein (LDL). Orticumab specifically inhibits oxidized low-density lipoproteins (oxLDL). Orticumab involves in modulation of autoimmune responses against oxLDL, improves atherosclerosis in animal model. Orticumab also can be used for research of psoriasis improvement .

HY-P99763

Ociperlimab BGB-A1217	Inhibitory Antibodies	Cancer
Ociperlimab is a humanized IgG1 anti-TIGIT antibody. Ociperlimab binds to the extracellular domain of human TIGIT with high affinity (K_D = 0.135 nM). Ociperlimab blocks the interaction between TIGIT and its ligands PVR or PVR-L2. Ociperlimab can be used in research of cancer .

HY-P99614

Fazpilodemab BFKB8488A	FGFR	Metabolic Disease
Fazpilodemab (BFKB8488A) is a humanized, agonistic, bispecific antibody targeting fibroblast growth factor receptor 1c (FGFR1c) and Klothoβ. Fazpilodemab can be used for the research of type 2 diabetes mellitus (T2DM) or nonalcoholic fatty liver disease (NAFLD) .

HY-P990022

Prafnosbart DS-6016A	Inhibitory Antibodies	Metabolic Disease
Prafnosbart (DS-6016A) is an IgG1-kappa, anti-ACVR1 (activin A receptor type 1, ACVRLK2, ALK2, ACVR1A, SKR1) humanized monoclonal antibody. Prafnosbart can be used for bone metabolism disorders research .

HY-P99590A

Sotatercept (mIgG2a)	Inhibitory Antibodies	Cardiovascular Disease
Sotatercept (mIgG2a) has direct cardioprotective actions, which reduces right ventricular (RV) remodeling and improves function in a pulmonary artery banding (PAB) mouse model .

HY-P99309

Pagibaximab BSYX-A 110; Anti-S. Epidermidis LTA Recombinant Antibody	Bacterial	Infection
Pagibaximab is a chimeric IgG1 antibody recognizing the surface component lipoteichoic acid of S. aureus and S. epidermidis. Pagibaximab can be used to prevent staphylococcal sepsis .

HY-145642

Masavibart ZRC3308-A7	SARS-CoV	Infection
Masavibart (ZRC3308-A7) is an anti-SARS-CoV-2 monoclonal antibody (IgG1 type). Masavibart shows good binding affinity to a non-competing epitope on the RBD of the SARS-CoV-2 spike protein. Masavibart can be used in combination with ZRC3308-B10 (HY-145643) at a ratio of 1:1, which is effective for the prevention of COVID-19 and the early stage of COVID-19 before the development of severe disease .

HY-P99619

Finotonlimab SCT-I10A	PD-1/PD-L1	Cancer
Finotonlimab (SCT-I10A) is a recombinant humanised IgG PD-1 antibody. Finotonlimab has the potential for solid tumors or lymphomas research .

HY-P9927A

Anti-Human IL-17A	Interleukin Related	Inflammation/Immunology Cancer
Anti-Human IL-17A is a fully human anti-interleukin-17A monoclonal antibody. Anti-Human IL-17A can be used for research in psoriasis pathogenesis .

HY-P99837

Dafsolimab SPV-T3a	CD3	Infection
Dafsolimab (SPV-T3a) is an IgG2a murine monoclonal antibody (anti-CD3). Dafsolimab can induce cell death through modulation and activation of the CD3/T cell receptor complex. Dafsolimab can be used for the research of graft-versus-host disease (GVHD) .

HY-P99593

Sofituzumab vedotin DMUC5754A	Antibody-Drug Conjugates (ADCs)	Cancer
Sofituzumab vedotin (DMUC5754A) is a MMAE-containing anti-MUC16 antibody-drug conjugate (ADC) with a protease-cleavable linker. Sofituzumab vedotin can be used for the research of cancer .

HY-P99189

Cixutumumab IMC-A12; NSC742460	Inhibitory Antibodies	Cancer
Cixutumumab (IMC-A12) is a human anti-IGF-1R monoclonal antibody with high affinity that inhibits ligand-dependent receptor activation and downstream signaling. Cixutumumab also mediates the internalization and degradation of IGF-IR. Cixutumumab shows broad-spectrum anti-tumour activity and can be used in studies of cancers such as lung cancer, malignancies, leukaemia, non-small cell lung cancer and prostate cancer .

HY-P99231

Edrecolomab Panorex; CO17-1A	Inhibitory Antibodies	Cancer
Edrecolomab (Panorex) is a murine monoclonal antibody to the cell-surface glycoprotein 17-1A, expressed on epithelial tissues and on various carcinomas. Edrecolomab shows anti-tumor activity and can be used in colorectal carcinoma research .

HY-P99544

Tagitanlimab HBM-9167; KL-A167	PD-1/PD-L1	Cancer
Tagitanlimab (HBM-9167) is a humanized anti-PD-L1 antibody (IgG1κ type). Tagitanlimab selectively blocks the interaction of PD-L1 and PD-1. Tagitanlimab has the potential to be studied in recurrent or metastatic nasopharyngeal carcinoma (NPC) .

HY-P99637

Gedivumab MHAA4549A; RG7745	Influenza Virus	Infection
Gedivumab (MHAA4549A; RG7745) is a human monoclonal antibody that targets influenza A virus (IAV) with high specificity and binds to the highly conserved stem region of the IAV haemagglutinin protein, thereby preventing haemagglutinin maturation and blocking haemagglutinin-mediated membrane fusion in the intranucleosome. Gedivumab can be used in IAV infection disease studies .

HY-P99699

Lesofavumab

MHAB5553A; RG70026
Influenza Virus Infection

Lesofavumab (MHAB5553A) is a human IgG1κ anti-influenza B virus antibody .

HY-P99897

Sampeginterferon beta-1a BCD-054	Inhibitory Antibodies	Others
Sampeginterferon beta-1a (BCD-054) is a pegylated IFNβ-1a. Sampeginterferon beta-1a can be used for research against remitting multiple sclerosis .

HY-P99959

Unasnemab MT-3921; rH116A3	Inhibitory Antibodies	Neurological Disease
Unasnemab (MT-3921) is a humanised IgG1 monoclonal antibody that binds to repulsive guidance molecule A (RGMa). Unasnemab improves locomotor function and promotes neuroregeneration and can be used for the research of spinal cord injury .

HY-P99861

Peginterferon lambda-1a

BMS-914143
IFNAR Others

Peginterferon lambda-1a (BMS-914143) is a monoclonal antibody targeting IFNLR1 and consists of IFNL1 conjugated to pegol .

HY-P990005

Mouse IgG2a Fc, Isotype Control	Inhibitory Antibodies	Others
Mouse IgG2a Fc, Isotype Control, is a Fc fragment of mouse IgG2a only and does not contain the Fab fragments. The molecular mass is about 34 kDa.

HY-P99593A

Sofituzumab vedotin (solution) DMUC5754A (solution)	Antibody-Drug Conjugates (ADCs)	Cancer
Sofituzumab vedotin (DMUC5754A) (solution) is an antibody-drug conjugate (ADC) that contains the humanized IgG1 anti-MUC16 monoclonal antibody and a potent anti-mitotic agent, monomethyl auristatin E (MMAE), linked through a protease-cleavable linker .

HY-P99124

Anti-Mouse CD3 Antibody (17A2)

CD3 Inflammation/Immunology

Anti-Mouse CD3 Antibody is an anti-mouse CD3 IgG2b antibody inhibitor derived from the host Rat.
HY-P99138

Anti-Mouse IL-1a Antibody (ALF-161)

Integrin Inflammation/Immunology

Anti-Mouse IL-1a Antibody is an anti-mouse IL-1a IgG1 antibody inhibitor derived from host Armenian Hamster.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-125833

Alpha-Naphthoflavone 5 Publications Verification	Flavonoids Flavones Source classification Indigofera heterantha Wall. ex Brand. Plants Compositae Disease Research Fields Cancer	Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis
Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis .

HY-W011474

Geranylgeraniol	Natural Products Microorganisms	NF-κB
Geranylgeraniol is an orally acitve vitamin K₂ sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model .

HY-P2274

Argifin	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Parasite
Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC₅₀s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively .

HY-N8356A

9-cis-Vitamin A palmitate 9-cis-Retinyl palmitate	Classification of Application Fields Terpenoids Source classification Other Diseases Diterpenoids Endogenous metabolite Disease Research Fields	Endogenous Metabolite
9-cis-Vitamin A palmitate (9-cis-Retinyl palmitate) is a 9-cis isomer formed by vitamin A palmitate in corn flakes. 9-cis-Vitamin A palmitate has a biological activity of 26% of all-trans-vitamin A palmitate, the most biologically ac-tive form of vitamin A .

HY-N11799

Neochilenin 3-O-Methylquercetin 4′-O-glucoside	Structural Classification Flavonoids Source classification Plants Compositae Other Flavonoids	Others
Neochilenin (3-O-Methylquercetin 4 '-O-glucoside) is a glycoside of 3-O-methylquercetin, which can be isolated from the sub-family Cereoideae (Cactaceae). .

HY-N10192

Aculene D	Infection Microorganisms Classification of Application Fields Terpenoids Sesquiterpenes Source classification Disease Research Fields	Endogenous Metabolite Bacterial
Aculene D, a fungal metabolite, shows quorum sensing (QS) inhibitory activity against Chromobacterium violaceum CV026, and could significantly reduce violacein production in N-hexanoyl-l-homoserine lactone (C6-HSL) induced C. violaceum CV026 cultures at sub-inhibitory concentrations .

HY-N0662

Amentoflavone 5+ Cited Publications Didemethyl-ginkgetin	Structural Classification Flavonoids Classification of Application Fields Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Disease Research Fields Selaginella tamariscina (P. Beauv.) Spring Cancer	Reactive Oxygen Species Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase .

HY-B0504S

Creatinine-d3 NSC13123-d<sub>3sub>	Classification of Application Fields Metabolic Disease Disease Research Fields	Endogenous Metabolite
Creatinine-d₃ is a deuterium labeled Creatinine. Creatinine is a break-down product of creatine phosphate in muscle[1].

HY-111954

(+)-Erinacin A Erinacine A	Structural Classification Microorganisms Terpenoids Diterpenoids	Others
(+)-Erinacin A is an anticancer compound that can be isolated from the mushroom Hericium erinaceum. (+)-Erinacin A has the capacity to trigger cancer cell death dependent on the production of reactive oxygen species (ROS). (+)-Erinacin A has anticancer and neuroprotective activity .

HY-134428

Arachidonoyl coenzyme A lithium	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Arachidonoyl coenzyme A lithium is an unsaturated fatty acyl coenzyme A, formed by the condensation of the thiol group of coenzyme A with the carboxyl group of arachidonic acid .

HY-134424

Propionyl coenzyme A lithium	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Propionyl coenzyme A lithium, a coenzyme A derivative of propionic acid, is an important metabolic intermediate formed by the thioester bond between coenzyme A and propionic acid. The breakdown and production of Propionyl coenzyme A lithim is important for the metabolism of organisms .

HY-N3226

Myricananin A

Source classification Myrica nagi Plants Myricaceae

NO Synthase

Myricananin A is a colorless needle that has inhibitory effect on iNOS .

HY-117175

Pandamarilactonine A (+)-Pandamarilactonine A	Structural Classification Alkaloids Pandanus amaryllifolius Roxb. Other Alkaloids Source classification Plants Pandanaceae	Others
Pandamarilactonine A converted from Norpandamarilactonine-A of (S)-prolinol .

HY-N8488

Anhydro-6-epiophiobolin A	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Disease Research Fields	Others
Anhydro-6-epiophiobolin A, an analog of Ophiobolin A, is a potent inhibitor of photosynthesis (I₅₀s of 6.1 and 1 mM for photosynthesis in Chlorella and Spinach, respectively) .

HY-N10509

Blood-group A trisaccharide A-Trisaccharide	Structural Classification Natural Products Polysaccharides Classification of Application Fields Animals Other Diseases Disease Research Fields Saccharides	Others
Blood-group A trisaccharide (A-Trisaccharide) is a oligosaccharide present in the urine of blood group A secretors .

HY-N8488A

Anhydroophiobolin A	Classification of Application Fields Other Diseases Disease Research Fields	Others
Anhydroophiobolin A is a potent inhibitor of photosynthesis with IC₅₀s of 77 and 14 mM in the photosynthesis of chlorella and spinach, respectively. Anhydroophiobolin A is an analog of Ophiobolin A .

HY-N3776

Dorsmanin A	Structural Classification Monophenols Source classification Phenols Plants Moraceae Dorstenia mannii Hook.f.	Others
Dorsmanin A is a prenylated flavonoid from the twigs of Dorstenia mannii .

HY-141474

Glutaryl coenzyme A lithium	Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Biochemical Assay Reagents
Glutaryl coenzyme A lithium is a Glutaryl coenzyme A derivative. Glutaryl coenzyme A is an important endogenous metabolites. Glutaryl coenzyme A lithium can be used in HMG-CoA or Glutaryl-CoA related experiment.

HY-118593

A2315A Madumycin II; Antibiotic A 2315A	Structural Classification Natural Products Microorganisms Source classification	Antibiotic
A2315A (Madumycin II) is an alanine-containing streptogramin A antibiotic. A2315A is a potent peptidyl transferase center (PTC) inhibitor. A2315A inhibits the ribosome prior to the first cycle of peptide bond formation .

HY-N6595

Lucidone A	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Others
Lucidone A is a lanostanoid isolated from the fruiting bodies of G. resinaceum. lucidone A showed inhibitory effects against the increase of ALT and AST levels in HepG2 cells induced by H2O2 compared to a control group in the range of their maximum non-toxic concentration (MNTC) .

HY-138146

4-Dehydrowithaferin A 4-oxo Withaferin A	Quinones Classification of Application Fields Source classification Benzene Quinones Withania somnifera Plants Solanaceae Disease Research Fields Cancer	Others
4-Dehydrowithaferin A is the analogue of withaferin A. Withaferin A is a withanolide isolated from Withania somnifera. 4-Dehydrowithaferin A has the potential for the research of multiple myeloma .

HY-W596782

Chaetochromin A Chaetochromin	Structural Classification Natural Products Microorganisms Source classification	Others
Chaetochromin A (Compound 1) is a fungal metabolite. Chaetochromin A shows inhibitory effect on botulinum neurotoxin serotype A (BoNT A) (IC₅₀= 24.6 μM) .

HY-W145690

Blood group A pentasaccharide A-Pentasaccharide	Structural Classification Natural Products Polysaccharides Classification of Application Fields Endogenous metabolite Inflammation/Immunology Disease Research Fields Saccharides	Others
Blood group A pentasaccharide (A-Pentasaccharide), an oligosaccharide in urine, can inhibit the binding of anti-A antibody to blood group A substance .

HY-103398

Nanaomycin C	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Disease Research Fields Other Antibiotics	Biochemical Assay Reagents
Nanaomycin C is an amide of nanaomycin A .

HY-N12044

Asparanin A	Structural Classification Polysaccharides Liliaceae Source classification Plants Saccharides Asparagus officinalis L.	Apoptosis
Asparanin A is an apoptosis inducer with anticancer activity. Asparanin A induces cell cycle arrest in the G0/G1 phase through mitochondria and PI3K/AKT signaling pathways, inhibiting cancer cell growth. Asparanin A also demonstrated in vivo efficacy in a mouse xenograft model of Ishikawa endometrial carcinoma, significantly inhibiting tumor growth .

HY-134425

β-Methylcrotonyl coenzyme A lithium	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
β-Methylcrotonyl coenzyme A lithium is an intermediate in leucine metabolism and can be used as a substrate to study the specificity and kinetics of β-methylcrotonyl coenzyme A carboxylase (MCCase) .

HY-N10352

4-epi-Withaferin A	Classification of Application Fields Source classification Withania somnifera Plants Solanaceae Disease Research Fields Steroids Cancer	Others
4-epi-Withaferin A (compound 28) is the analogue of Withaferin A. 4-epi-Withaferin A enhances cytotoxicity and cytoprotective heat-shock-inducing activity (HSA). 4-epi-Withaferin A has the potential for the research of protein aggregation-associated diseases by stimulating cellular defense mechanisms .

HY-134438

Hexanoyl coenzyme A trilithium	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Hexanoyl coenzyme A trilithium is a hexanoyl-based medium-chain fatty acyl coenzyme A that is present in all organisms. Hexanoyl coenzyme A trilithium can be used as a precursor for cannabinoid biosynthesis and acts as a competitive inhibitor of medium-chain acyl coenzyme A dehydrogenase (MCAD) .

HY-N7332

Pepluanin A	Structural Classification Terpenoids Source classification Euphorbia peplus Linn. Diterpenoids Euphorbiaceae Plants	P-glycoprotein
Pepluanin A is a natural compound isolated from Euphorbia peplus L. Pepluanin A shows a very high activity for a jatrophane diterpene, outperforming Cyclosporin A by a factor of at least 2 in the inhibition of Pgp-mediated Daunomycin (HY-13062A) transport ^[1]

HY-N10355

27-TBDMS-4-Dehydrowithaferin A	Quinones Classification of Application Fields Source classification Benzene Quinones Withania somnifera Plants Solanaceae Disease Research Fields Steroids Cancer	Apoptosis
27-TBDMS-4-Dehydrowithaferin A, a withaferin A derivative, exhibits potent antiproliferative effects on the tumor cells.27-TBDMS-4-Dehydrowithaferin A induces tumor cells apoptosis. 27-TBDMS-4-Dehydrowithaferin A is a anticancer agent .

HY-134136

Octanoyl Coenzyme A	Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Octanoyl coenzyme A is a fatty acyl coenzyme A derivative. Octanoyl coenzyme A can inhibit citrate synthase (CS) and glutamate dehydrogenase (GDH) with IC₅₀ values of 0.4-1.6 mM .

HY-N6677

β-Apo-8'-carotenal Apocarotenal	Other Terpenoids other families Classification of Application Fields Terpenoids Source classification Plants Disease Research Fields Cancer	Cytochrome P450
β-Apo-8'-carotenal (Apocarotenal), a provitamin A carotenoid, is an inducer of CYPlA1 and CYPlA2 in rat. β-Apo-8'-carotenal is present in many fruits and vegetables .

HY-134426

DL-β-Hydroxybutyryl coenzyme A lithium	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
DL-β-Hydroxybutyryl coenzyme A lithium is an intermediate in the fermentation of butyric acid and the metabolism of lysine and tryptophan, and is produced from β-hydroxybutyric acid by short-chain-CoA synthase .

HY-N0365

Sennoside A 1 Publications Verification	Infection Quinones Structural Classification Classification of Application Fields Leguminosae Anthraquinones Source classification Folium Sennae Cassia angustifolia Vahl Cassia acutifolia Del. Plants Disease Research Fields	HIV
Sennoside A is an anthraquinone glycoside found in senna (Cassia angustifolia). Sennoside A is an HIV-1 inhibitor (IC₅₀=3.8 μM) that inhibits HIV-1 replication. Sennoside A also inhibits HIV-1 reverse transcriptase (RT)-related DNA polymerase (RDDP) and ribonuclease H (Ribonuclease H) with IC₅₀s of 1.9 μM and 5.3 μM, respectively .

HY-P3107

Homodestcardin	Structural Classification Microorganisms Classification of Application Fields Cyclopeptides Source classification Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
Homodestcardin, a destruxinbased cyclodepsipeptide, is a immunosuppressant. Homodestcardin, a fungal metabolite, displays pronounced activities against concanavalin A (Con A) activation, with an IC₅₀ value of 0.86 μM .

HY-N11939

Kadsuralignan A	Schisandra lancifolia (Rehd. et Wils.) A. C. Smith Structural Classification Source classification Lignans Phenylpropanoids Plants Schisandraceae	HIV
Kadsuralignan A (compound 1) is a dibenzocyclooctadiene lignan isolated from the leaves and stems of Schisandra lancifolia. Kadsuralignan A has anti-HIV activity with EC₅₀=2.23 μg/mL .

HY-147406

Tonlamarsen ION-904	Cardiovascular Disease Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Tonlamarsen is a angiotensinogen synthesis reducer, with antihypertensive activity .

HY-N8805

Nortrachelogenin-8'-O-β-glucoside	Ranunculaceae Phenols Polyphenols Plants Pulsatilla cernua (Thunb.) Bercht. et Opiz.	Others
Nortrachelogenin-8'-O-β-glucoside is a natural product that can be isolated from the dried roots of Pulsatilla koreana. Nortrachelogenin-8'-O-β-glucoside inhibits cancer cell proliferation and reduces hormone dependence .

HY-N12179

Brevianamide M	Structural Classification Alkaloids Human Gut Microbiota Metabolites Microorganisms Other Alkaloids Source classification Endogenous metabolite	Bacterial
Brevianamide M (compound 4) is a metabolite of Aspergillus versicolor. This is an endophytic fungus isolated from the marine brown alga Sargassum. Brevianamide M has antimicrobial activity against Escherichia coli and Staphylococcus aureus .

HY-15127

Isotretinoin 4 Publications Verification 13-cis-Retinoic acid	Structural Classification Classification of Application Fields Terpenoids Source classification Diterpenoids Endogenous metabolite Disease Research Fields Cancer	RAR/RXR Endogenous Metabolite Autophagy
Isotretinoin (13-cis-Retinoic acid) is an orally active vitamin A derivative and is often be used for the research of severe acne. Isotretinoin also shows anticancer activity .

HY-N0035

Arctigenin 5+ Cited Publications (-)-Arctigenin	Structural Classification Neurological Disease Classification of Application Fields Anti-aging Source classification Lignans Metabolic Disease Plants Compositae Caesalpinia magnifoliolata Metc. Endogenous metabolite Infection Human Gut Microbiota Metabolites Phenylpropanoids Inflammation/Immunology Disease Research Fields Cancer	MMP Influenza Virus Autophagy Apoptosis
Arctigenin ((-)-Arctigenin), a biologically active lignan, can be used as an antitumor agent. Arctigenin exhibits potent antioxidant, anti-inflammatory and antiviral (influenza A virus) activities. Arctigenin can be used for the research of metabolic disorders, and central nervous system dysfunctions .

HY-N11770

Rhamnetin 3-O-β-D-glucopyranoside	Structural Classification Flavonoids Flavones Source classification Polygalaceae Polygala sibirica Linn. Plants	Others
Rhamnetin 3-O-β-D-glucopyranoside is a flavonoid, that can be isolated from the roots of Polygala sibirica L. (Polygalaceae) .

HY-N8556

3,4,5-Trimethoxyphenyl-(6'-O-galloyl)-O-β-D-glucopyranoside	Structural Classification Source classification Phenols Polyphenols Plants Moraceae Taxotrophis ilicifolia S. Vidal	Others
3,4,5-Trimethoxyphenyl-(6' -o-galloyl) -o-β-d-Glucopyranoside is a phenylpropanoside derived from natural the bark of Streblus ilicifolius (Vidal) .

HY-N7346

Lucidadiol	Triterpenes Structural Classification Microorganisms Terpenoids Source classification	HSV Cholinesterase (ChE)
Lucidadiol is a natural compound isolated from Ganoderma lucidum. Lucidadiol exhibits acetylcholinesterase-inhibitory activity, with IC₅₀ values of 31 μM. Lucidadiol shows antiviral activity against influenza virus type A and HSV type 1 .

HY-N12360A

2,3-Dehydrosilybin B	Structural Classification Flavonols Flavonoids Source classification Cyamopsis tetragonoloba (L.) Taub. Plants Compositae	Others
2,3-Dehydrosilybin B is an enantiomer formed by the oxidation of the natural flavonolignans silybin A .

HY-N12110

SMU-CX1	Apocynaceae Structural Classification Alkaloids Other Alkaloids Source classification Plants	Toll-like Receptor (TLR) SARS-CoV
SMU-CX1 is a specific TLR3 inhibitor (IC₅₀: 0.11 μM) with IC₅₀ ranging from 0.14-0.33 μM against multiple influenza A virus subtypes. SMU-CX1 inhibits the viral PB2 and NP proteins with an IC₅₀ of 0.43 μM for SARS-CoV-2 activity. SMU-CX1 also inhibits inflammatory factors in host cells, including IFN-β, IP-10, and CCL-5 .

HY-N0505

Rosiridin	Other Monoterpenes Rhodiola rosea Linn. Terpenoids Source classification Crassulaceae Plants	Monoamine Oxidase
Rosiridin inhibits MAO A and MAO B with potential beneficial effect in depression and senile dementia. Rosiridin shows an inhibition of 83.8% against MAO B at 10 μM (pIC₅₀=5.38) .

HY-N3421

Koaburaside	Structural Classification Eucommia ulmoides Oliver Source classification Eucommiaceae Plants Saccharides Monosaccharides	Interleukin Related TNF Receptor Influenza Virus
Koaburaside is a cytoprotective and anti-inflammatory natural compound. Koaburaside shows antioxidant activity with an IC₅₀ of 9.0 μM for DPPH-free radical scavenging assay. Koaburaside inhibits histamine release and expressions of IL-6 and TNF-α in human mast cells. Koaburaside also effectively inhibits influenza A neuraminidase .

HY-N3745

(-)-(7R, 8S)-dihydrodehydrodiconiferyl alcohol	Structural Classification Hedyotis uncinella Hook. et Arn. Source classification Lignans Rubiaceae Phenylpropanoids Plants	Others
(-)-(7R, 8S)-dihydrodehydrodiconiferyl alcohol (compound 10) is a lignan isolated from Hedyotis uncinella .

HY-113462

α-Carotene	Structural Classification Classification of Application Fields Daucus carota Linn. var. sativa Hoffm. Source classification Plants Food Research Other Terpenoids Microorganisms Terpenoids Pigments Umbelliferae Disease Research Fields Cancer	Others
α-Carotene, a precursor of vitamin A, is used as an anti-metastatic agent or as an adjuvant for anti-cancer agents. α-Carotene is isolated from yellow-orange and dark-green vegetables .

Cat. No.	Product Name	Chemical Structure

HY-16760S

9-cis-Retinol acetate-d5

9-cis-Retinol acetate-d₅ is the deuterium labeled 9-cis-Retinol acetate. 9-cis-Retinol acetate is a retinal derivative[1][2].

HY-10844S1

Pretomanid-d5
Pretomanid-d₅ is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.

HY-B1203AS

Fludrocortisone acetate-d5

Fludrocortisone acetate-d₅ is deuterium labeled Fludrocortisone acetate.
HY-W102356S2

Phenethyl acetate-d5

Phenethyl acetate-d₅ is deuterated labeled Phenethyl acetate.

HY-B0579S2

Cyclosporin A acetate-d4
Cyclosporin A acetate-d₄ (Cyclosporine A acetate-d₄; Ciclosporin A acetate-d₄) is a deuterium labeled Cyclosporin A (HY-B0579) . Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC₅₀ of 5 nM . Cyclosporin A also inhibits CD11a/CD18 adhesion .

HY-N0679S4

Retinyl acetate-d4
Retinyl acetate-d₄ is the deuterium labeled Retinyl acetate[1]. Retinyl acetate is a synthetic acetate ester form derived from retinol and has potential antineoplastic and chemo preventive activities[2].

HY-B0469S

Medroxyprogesterone acetate-d3
Medroxyprogesterone acetate-d₃ is deuterium labeled Medroxyprogesterone acetate. Medroxyprogesterone acetate is a widely used synthetic steroid by its interaction with progesterone, androgen and glucocorticoid receptors[1].

HY-13777S

Zoledronic acid-d5
Zoledronic acid-d₅ is deuterated labeled Zoledronic Acid (HY-13777). Zoledronic Acid (Zoledronate) is a third-generation bisphosphonate (BP), with potent anti-resorptive activity. Zoledronic Acid inhibits the differentiation and apoptosis of osteoclasts. Zoledronic Acid also has anti-cancer effects .

HY-W102356S

Phenethyl acetate-d3

Phenethyl acetate-d₃ is the deuterium labeled Phenethyl acetate[1].

HY-109592S

Imidaprilate-d5
Imidaprilate-d₅ is deuterium labeled Imidaprilate. Imidaprilate is an active metabolite of TA-6366, acts as a potent angiotensin converting enzyme (ACE) inhibitor, with an IC50 of 2.6 nM, and is used in the research of hypertensive disease.

HY-B1710S

Norethindrone acetate-d8
Norethindrone acetate-d₈ is the deuterium labeled Norethindrone acetate. Norethindrone acetate is a female hormone used for the research of endometriosis[1]. Norethindrone acetate-d8 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B0184S1

Felbamate-d5
Felbamate-d₅ is the deuterium labeled Felbamate[1]. Felbamate (W-554) is a potent nonsedative anticonvulsant whose clinical effect may be related to the inhibition of N-methyl-D-aspartate (NMDA)[2][3].

HY-W016481S

4-Methoxybenzyl acetate-d3

4-Methoxybenzyl acetate-d₃ is deuterated labeled cis-3-Hexenyl Acetate.

HY-17621S

Sparsentan-d5
Sparsentan-d₅ is deuterium labeled Sparsentan. Sparsentan (RE-021) is a highly potent dual angiotensin II and endothelin A receptor antagonist with Kis of 0.8 and 9.3 nM, respectively[1].

HY-W015304S

2-Ethylhexyl acetate-d17

2-Ethylhexyl acetate-d₁₇ is the deuterium labeled 2-Ethylhexyl acetate[1].
HY-W343292S1

2-Methylbutyl acetate-d3

2-Methylbutyl acetate-d₃ is deuterated labeled 2-Methylbutyl acetate.

HY-16560S

Camptothecin-d5

Camptothecin-d₅ is the deuterium labeled Camptothecin. Camptothecin (CPT), a kind of alkaloid, is a DNA topoisomerase I (Topo I) inhibitor with an IC50 of 679 nM[1]. Camptothecin (CPT) exhibits powerful antineoplastic activity against colorectal, breast, lung and ovarian cancers, modulates hypoxia-inducible factor-1α (HIF-1α) activity by changing microRNAs (miRNA) expression patterns in human cancer cells[2][3].

HY-B0715S2

Pentoxifylline-d5

Pentoxifylline-d₅ is the deuterium labeled Pentoxifylline. Pentoxifylline (BL-191), a haemorheological agent, is an orally active non-selective phosphodiesterase (PDE) inhibitor, with immune modulation, anti-inflammatory, hemorheological, anti-fibrinolytic and anti-proliferation effects. Pentoxifylline can be used for the research of peripheral vascular disease, cerebrovascular disease and a number of other conditions involving a defective regional microcirculation[1][2][3].

HY-14649S4

Retinoic acid-d5

Retinoic acid-d₅ is the the deuterium labeled Retinoic acid (HY-14649). Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC₅₀s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with K_d of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha ^[5].

HY-107819S

5α-Cholestan-3β-ol-d5

5α-Cholestan-3β-ol-d₅ is the deuterium labeled 5α-Cholestan-3β-ol. 5α-Cholestan-3β-ol is a derivitized steroid compound[1].

HY-N0573S

Umbelliferone-d5
Umbelliferone-d₅ is the deuterium labeled Umbelliferone. Umbelliferone (7-Hydroxycoumarin), a natural product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent.

HY-W022036S

2-Ethoxyphenol-d5

2-Ethoxyphenol-d₅ is the deuterium labeled 2-Ethoxyphenol[1].
HY-66005S5

Acetaminophen-d5

Acetaminophen-d₅ is deuterated-labeled Acetaminophen.

HY-16562AS

Irinotecan-d5 hydrochloride
Irinotecan-d₅ hydrochloride is deuterated labeled Irinotecan hydrochloride (HY-16562A). Irinotecan hydrochloride ((+)-Irinotecan hydrochloride) is a topoisomerase I inhibitor mainly used to treat colon cancer and rectal cancer .

HY-B1207S

Urethane-d5
Urethane-d₅ is the deuterium labeled Urethane. Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress bacterial, protozoal, sea urchin egg, and plant tissue growth in vitro[1].

HY-77839S

Cortodoxone-d5

Cortodoxone-d₅ is the deuterium labeled Cortodoxone.

HY-14814S

Delafloxacin-d5
Delafloxacin-d₅ is deuterium labeled Delafloxacin. Delafloxacin (RX-3341; WQ-3034; ABT492) is a broad-spectrum fluoroquinolone antibiotic. Delafloxacin has a broad spectrum of activity that includes drug-resistant Staphylococcus aureus, Streptococcus pneumoniae, and Klebsiella pneumonia[1].

HY-13636S1

Fulvestrant-d5

Fulvestrant-d5 is a isotope of Fulvestrant .
HY-B1342S4

Retinol-d5

Retinol-d₅ is the deuterium labeled Retinol[1].

HY-W014612S

Eugenol acetate-d3
Eugenol acetate-d₃ is deuterated labeled Decyl aldehyde (HY-W012570). Decyl aldehyde is a simple ten-carbon aldehyde. Decyl aldehyde is a bacterial luciferase substrate.

HY-B0200S

Cephalexin-d5
Cephalexin-d₅ is deuterium labeled Cephalexin. Cephalexin (Cefalexin; Cephacillin) is a potent, orally active and the first-generation cephalosporin antibiotic. Cephalexin kills gram-positive and some gram-negative bacteria by disrupting the growth of the bacterial cell wall. Cephalexin monohydrate is used for the research of pneumonia, strep throat, and bacterial endocarditis, et al[1].

HY-B0178AS1

Guanidine-d5 hydrochloride
Guanidine-d₅ (hydrochloride) is the deuterium labeled Guanidine hydrochloride[1]. Guanidine hydrochloride (Guanidinium chloride) a strong chaotrope, is also a strong denaturant of proteins[2][3].

HY-B1214S

Prednisolone acetate-d8
Prednisolone acetate-d₈ is the deuterium labeled Prednisolone acetate. Prednisolone acetate (Prednisolone 21-acetate) is an adrenal cortico hormones, with anti-inflammatory, anti-allergic and immune suppressive effects.

HY-N0570S1

Hydroxytyrosol-d5
Hydroxytyrosol-d₅ is the deuterium labeled Hydroxytyrosol. Hydroxytyrosol (DOPET) is a phenolic compound drawn from the olive tree and its leaves with anti-oxidant, anti-atherogenic, anti-thrombotic, antimicrobial, anti-inflammatory and anti-tumour effects[1][2].

HY-B0941S

6-Benzylaminopurine-d5

6-Benzylaminopurine-d₅ is the deuterium labeled 6-Benzylaminopurine. 6-Benzylaminopurine is a cytokinin[1].
HY-B0878S

Halobetasol propionate-d5

Halobetasol propionate-d₅ is deuterium labeled Halobetasol (propionate).

HY-B1290S2

2-Phenylethanol-d5

2-Phenylethanol-d₅ is the deuterium labeled 2-Phenylethanol[1]. 2-Phenylethanol (Phenethyl alcohol), extracted from rose, carnation, hyacinth, Aleppo pine, orange blossom and other organisms, is a colourless liquid. It has a pleasant floral odor and also an autoantibiotic produced by the fungus Candida albicans[2]. It is used as an additive in cigarettes and also used as a preservative in soaps due to its stability in basic conditions.

HY-B1832S

Prednisone acetate-d3
Prednisone acetate-d₃ is the deuterium labeled Prednisone acetate. Prednisone acetate (Prednisone 21-acetate), the acetate salt form of prednisolone, is a glucocorticoid receptor agonist with anti-inflammatory and immunomodulating properties[1].

HY-W015710S

cis-3-Hexenyl Acetate-d2

cis-3-Hexenyl Acetate-d₂ is deuterated labeled 2-Benzylideneheptanal.
HY-D0272S

2,3,4-Trihydroxybenzophenone-d5

2,3,4-Trihydroxybenzophenone-d₅ is the deuterium labeled 2,3,4-Trihydroxybenzophenone[1].
HY-B0346S

Propylthiouracil-d5

Propylthiouracil-d₅ is the deuterium labeled Propylthiouracil. Propylthiouracil (6-Propyl-2-thiouracil) is a thyroperoxidase and 5'-deiodinase inhibitor.

HY-12222S

Obeticholic acid-d5
Obeticholic acid-d₅ is the deuterium labeled Obeticholic acid. Obeticholic acid (INT-747) is a potent, selective and orally active FXR agonist with an EC50 of 99 nM. Obeticholic acid has anticholeretic and anti-inflammation effect. Obeticholic acid also induces autophagy[1][2][3].

HY-12760S

Indoramin-d5

Indoramin-d₅ is deuterium labeled Indoramin, which is a piperidine antiadrenergic agent.

HY-14648S

Dexamethasone-d5

Dexamethasone-d₅ is the deuterium labeled Dexamethasone. Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18 expression on monocytes. Dexamethasone is highly effective in the control of COVID-19 infection. Dexamethasone inhibits production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses[1][2].

HY-17043S1

Loratadine-d5
Loratadine-d₅ is the deuterium labeled Loratadine. Loratadine (SCH-29851) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM. Loratadine has anti-dengue-virus (DENV) activity. Loratadine can inhibit immunologic release of inflammatory mediators.

HY-141642S

Triheptadecanoin-d5

Triheptadecanoin-d₅ is the deuterium labeled Triheptadecanoin[1].
HY-B0521S

Altrenogest-d5

Altrenogest-d₅ is the deuterium labeled Altrenogest. Altrenogest (Allyltrenbolone) is a progestogen structurally related to veterinary steroid trenbolone.

HY-N0623S

L-Tryptophan-d5
L-Tryptophan-d₅ is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].

HY-B0808S1

Oxaprozin-d5
Oxaprozin-d₅ is deuterium labeled Oxaprozin. Oxaprozin is an inhibitor of both COX-1 and COX-2 with IC50s of 2.2 μM and 36 μM for human platelet COX-1 and IL-1-stimulated human synovial cell COX-2, respectively. Oxaprozin also inhibits the activation of NF-κB.

HY-75054S

Abiraterone acetate-d4
Abiraterone acetate-d₄ is the deuterium labeled Abiraterone acetate. Abiraterone acetate (CB7630) is an oral, potent, selective, and irreversible inhibitor of CYP17A1 with antiandrogen activity. Abiraterone acetate is a proagent form of Abiraterone (CB7598).

Cat. No.	Product Name		Classification

HY-B0216S

Ethynyl Estradiol-d4 17α-Ethynylestradiol-d<sub>4sub>; Ethynylestradiol-d<sub>4sub>		Alkynes
Ethynyl Estradiol-d₄ is the deuterium labeled Ethynyl Estradiol. Ethynyl Estradiol (17α-Ethynylestradiol;Ethynylestradiol) is an orally bio-active estrogen used in almost all modern formulations of combined oral contraceptive pills. Ethynyl Estradiol-d4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B1710S

Norethindrone acetate-d8 19-Norethindrone acetate-d<sub>8sub>		Alkynes
Norethindrone acetate-d₈ is the deuterium labeled Norethindrone acetate. Norethindrone acetate is a female hormone used for the research of endometriosis[1]. Norethindrone acetate-d8 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-17413S

Zidovudine-d3 Azidothymidine-d<sub>3sub>; AZT-d<sub>3sub>; ZDV-d<sub>3sub>		Azide
Zidovudine-d₃ is the deuterium labeled Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection. Zidovudine increases CRISPR/Cas9-mediated editing frequency. Zidovudine-d3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

HY-50896S

Erlotinib-d6 CP-358774-d<sub>6sub>; NSC 718781-d<sub>6sub>; OSI-774-d<sub>6sub>		Alkynes
Erlotinib-d₆ (CP-358774 D6) is a deuterium labeled Erlotinib (CP-358774). Erlotinib is a directly acting inhibitor EGFR tyrosine kinase inhibitor with an IC50 of 2 nM for human EGFR[1]. Erlotinib-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B0110S

Gestodene-d6 SHB 331-d<sub>6sub>; WL 70-d<sub>6sub>		Alkynes
Gestodene-d₆is the deuterium labeled Gestodene. Gestodene(SHB 331) is a progestogen hormonal contraceptive[1][2]. Gestodene-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-G0018S

Norgestimate metabolite norelgestromin-d6 17-Deacetyl norgestimate-d<sub>6sub>; 17-Deacylnorgestimate-d<sub>6sub>		Alkynes
Norgestimate metabolite norelgestromin-d₆ is the deuterium labeled Norgestimate metabolite norelgestromin. Norelgestromin is a metabolite of Norgestimate, which is a progestin or synthetic progestogen. Norgestimate metabolite norelgestromin-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-50896S1

Erlotinib-13C6 CP-358774-¹³C<sub>6sub>; NSC 718781-¹³C<sub>6sub>; OSI-774-¹³C<sub>6sub>		Alkynes
Erlotinib- ¹³C₆ is a ¹³C-labeled Erlotinib. Erlotinib is a directly acting EGFR tyrosine kinase inhibitor, with an IC50 of 2 nM for human EGFR[1].

HY-12008S1

Erlotinib-13C6 hydrochloride CP-358774-¹³C<sub>6sub> hydrochloride; NSC 718781-¹³C<sub>6sub> hydrochloride; OSI-774-¹³C<sub>6sub> hydrochloride		Alkynes
Erlotinib- ¹³C₆ (hydrochloride) is the ¹³C labeled Erlotinib Hydrochloride[1]. Erlotinib Hydrochloride (CP-358774 Hydrochloride) inhibits purified EGFR kinase with an IC50 of 2 nM[2]. Erlotinib-13C6 (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-17413S1

Zidovudine-13C,d3 Azidothymidine-¹³C,d<sub>3sub>; AZT-¹³C,d<sub>3sub>; ZDV-¹³C,d<sub>3sub>		Azide
Zidovudine- ¹³C,d₃ is the ¹³C- and deuterium labeled Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection. Zidovudine increases CRISPR/Cas9-mediated editing frequency. Zidovudine-13C,d3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

HY-B0554S

Norethindrone-d6 Norethisterone-d<sub>6sub>		Alkynes
Norethindrone-d₆ is the deuterium labeled Norethindrone. Norethindrone is a female progestin approved by FDA for the treatment of endometriosis, uterine bleeding caused by abnormal hormone levels, and secondary amenorrhea. Norethindrone-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B0257S

Levonorgestrel-d8 D-Norgestrel-d<sub>8sub>		Alkynes
Levonorgestrel-d₈ is the deuterium labeled Levonorgestrel. Levonorgestrel is a synthetic progestogen used as an active ingredient in some hormonal contraceptives[1][2]. Levonorgestrel-d8 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B0216S2

Ethynyl Estradiol-13C2 17α-Ethynylestradiol-¹³C<sub>2sub>; Ethynylestradiol-¹³C<sub>2sub>		Alkynes
Ethynyl Estradiol- ¹³C₂ is the ¹³C-labeled Ethynyl Estradiol. Ethynyl Estradiol-13C2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-14605BS

Rasagiline-13C3 mesylate racemic AGN1135-¹³C<sub>3sub>; TVP1012-¹³C<sub>3sub> racemic		Alkynes
Rasagiline- ¹³C₃ (mesylate racemic) is a ¹³C-labeled Rasagiline mesylate racemic. Rasagiline mesylate racemic is a highly potent selective irreversible mitochondrial monoamine oxidase (MAO) inhibitor[1]. Rasagiline-13C3 (mesylate racemic) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-142706

MAO A/HDAC-IN-1		Alkynes
MAO A/HDAC-IN-1 is a dual?inhibitor?of monoamine oxidase A (MAO A) and HDAC. MAO A/HDAC-IN-1 can be used for glioma research . MAO A/HDAC-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-101532

6A-Azido-6A-deoxy-β-cyclodextrin β-CDN3; 6A-deoxy-6A-azido-β-cyclodextrin		Azide
6A-Azido-6A-deoxy-β-cyclodextrin (β-CDN3; 6A-deoxy-6A-azido-β-cyclodextrin) is a new water-soluble Schiff base ligand based on β-cyclodextrin (HY-107201). 6a-Azido-6a-deoxy-β-cyclodextrin can be used for biaqueous hydroformylation. β-cyclodextrin (βCD) has a unique affinity for Dexamethasone (HY-14648), and can be used as a topical osmotic enhancer to introduce it into the agent carrier system . 6A-Azido-6A-deoxy-β-cyclodextrin is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

HY-151212

BCP-T.A		Alkynes
BCP-T.A, a tunable heterocyclic electrophile, is a potent ferroptosis inducer by binding to GPX4 . BCP-T.A is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W749627

NO2A-Butyne		Alkynes
NO2A-Butyneis a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic NOTA derivative used for tumor pre-targeting. NO2A-Butyne can be used for conjugation of peptides and radionuclides.

HY-W717800A

NO2A-Azide trihydrochloride		Azide
NO2A-Azide (trihydrochloride)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic NOTA derivative used for tumor pre-targeting. NO2A-Azide (trihydrochloride) can be used for conjugation of peptides and radionuclides.

HY-139296

PP2A Cancerous-IN-1		Alkynes
PP2A Cancerous-IN-1 is a strong and potent CIP2A (Cancerous inhibitor of PP2A) and p-Akt inhibitor. PP2A Cancerous-IN-1 shows the most potent antiproliferative activities . PP2A Cancerous-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-145340

2'-O-Propargyl A(Bz)-3'-phosphoramidite		Alkynes
2'-O-Propargyl A(Bz)-3'-phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .

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Species:	Human (1512) Porcine (2) Rhesus Macaque (50) Rat (121) Bovine (2) Xenopus laevis (3) Cynomolgus (92) E.coli (11) Rabbit (9) Pig (9) Canine (25) Virus (617) Marmoset (3) Mouse (499) Cat (1) Dog (3) Staphylococcus aureus (8)
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Source:	HEK293 (1908) E. coli Cell-free (47) CHO (3) CHO (21) Sf9 insect cells (5) P. pastoris (57) Sf9 insect cells (348) E. coli (581)


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